What is Atherosclerosis - 1293 Words

Introduction Atherosclerosis is an inflammatory disease that causes formation of plaques under the intimal layer of the blood vessel wall. As the plaque grows and calcifies, it narrows the blood vessel lumen and decreases blood flow to the downstream tissue. Also, risk of plaque rupture increases. Plaque rupture leads to platelet adhesion that results in a thrombus, which occludes the artery. Occlusion of the coronary arteries results in myocardial infarction. Pathologies affecting small and medium sized arteries are the leading cause of death worldwide. Due to development of better treatments, mortality rates after myocardial infarction have decreased in the last decades (REF). However, replacement of the occluded artery is often necessary. The currently available options for these transplants are limited. The most frequently applied treatment for coronary artery occlusion is a bypass operation. During this operation, an autologous blood vessel (often a saphenous vein or a mammary artery) is use d to bypass the coronary artery. The use of these so-called autografts is invasive and may be limited due to previous harvesting and anatomical variability. Furthermore, atherosclerosis is often found in almost all blood vessels of the patient. The risk of occlusion of the autograft is high (Hasan et al., 2014). Developments in tissue engineering allow for the creation of new vascular grafts from synthetic or natural polymers and patient derived cells. Given the occurrence ofShow MoreRelatedWhat Is Atherosclerosis And Cancer?732 Words   |  3 PagesThis paper indicates a mechanism to target disease sites in diseases such as atherosclerosis and cancer, which are sources of TNFa. If a cell is engineered to seek TNFa sources like those in cancer and atherosclerosis, they could be utilized as a targeted therapy. In order to accomplish this a system of engineered proteins was utilized TNFa chimeric receptor (namedTNFR1chi), a previously engineered Ca2+-activated RhoA (named CaRQ), vesicular stomatitis virus glycoprotein G (VSVG), and thymidine kinaseRead MoreVascular Lymphatic System And Atherosclerosis1280 Words   |  6 Pages Vascular Lymphatic System/Atherosclerosis Jazmin Fontan Bryant Stratton College AHLT120: Anatomy and Physiology-1 Dr. Pamela K. Hannaman, MS, ND, CPC, CMRS, CCMA November 18, 2015 Narrowing and hardening of the artery walls causing buildup of fatty tissues (plaque), cholesterol and other substances, which may restrict blood flow is referred to as atherosclerosis. Having restriction of blood flow develops damage to a patients’ organs and also increases the risk of heart attacksRead MoreA Brief Note On Atherosclerosis And Its Effects On The Heart Essay1138 Words   |  5 Pages Definition of the disease Atherosclerosis is a disease dealing with the heart. This disease causes hardening and narrowing (or even blockage) of the arteries, which makes the arteries thicken. Accumulations of fat, calcium and plaque build up are all components of having this disease known as atherosclerosis. The accumulations of calcium, fat, and plaque build up quietly and slowly block the arteries, putting blood flow at an extremely high risk. Atherosclerosis is typically the source of heartRead MoreA Brief Note On Atherosclerosis And Cardiovascular System938 Words   |  4 PagesSYSTEMIC CIRCULATION: Atherosclerosis Cardiovascular system consists of the heart, blood vessels and the blood inside them. It’s responsible for transporting oxygen, nutrition and waste products throughout the body. The heart is the circulatory pump that transports blood to the entire body. Cardiovascular system has two circulations: systemic and the pulmonary circulations. Pulmonary circulation is the flow of blood between the heart and lungs. Pulmonary circulation starts when the deoxygenatedRead MoreWhat I Know About Anna Garcia1130 Words   |  5 Pagesthe floor, turned on its side with a couple of orange juice 2.5 ft away from her spilled on the floor and a footprint found near her front door. Luckily, the footprint and the blood stain on the floor and corner of the table belonged to her. Based on what I know, Anna Garcia died from a Diabetic coma caused by many other disorders affecting her cardiovascular, nervous, urinary, and digestive system. Her coma was most likely caused by dehydration, heart attack, ketoacidosis, and high blood sugarRead MoreHeart Disease : A Generic Term For Heart Conditions1619 Words   |  7 Pagestaken from the NHS website indicate that that there are 74,000 deaths each year and the cause of death for 1 in 6 men and 1 in 10 women. How the Blood Supply Works to the Heart. Figure 1 is an image of an Angiogram of a healthy heart and shows what a healthy heart should look like. The heart pumps blood that contain contains oxygen and it beats up to 100,000 times a day. It is coronary circulation that supplies blood to the muscle tissue of the heart. This is also called cardiac circulation andRead MoreOne Beat At a Time Essay1318 Words   |  6 Pagesleading it to be the number one disease today. As of this time comprehensive studies have been undertaken to research the causes and possible cures for cardio vascular diseases. Some of the common cardio vascular diseases today are arrhythmia, atherosclerosis, and congestive heart failure. Arrhythmia, commonly known as irregular heartbeat is one of the common cardio vascular diseases. Have you ever thought that your heart skipped a beat when in love; well for some people their heart skips a beat quiteRead MoreCellulose, Starch, Glycogen, Prion Disease and Cholesterol954 Words   |  4 Pagesrepeat unit. Cellulose is a lot stronger than starch. Starch is practically useless as a material, but cellulose is strong enough to make fibers from. Cellulose doesnt dissolve in water the way starch will, and doesnt break down as easily. 2. What is a prion disease? Why are they hard to detect and treat? Prion diseases belong to group of progressive conditions that affect the nervous system in humans and animals. Prion diseases impair brain function which cause memory changes, personalityRead MoreHigh Density Lipoprotein ( Ldl ) Levels Essay1612 Words   |  7 Pagesbody, which is optimal. The next concern I have from your results are your cholesterol levels. Your High Density Lipoprotein (HDL) levels are within the appropriate levels but your triglycerides and Low Density Lipoprotein (LDL) levels are way above what I would like them to be. A combination of all three of these numbers makes up your total cholesterol level, which is also high, due to your high levels of LDL and triglycerides. Your blood glucose is just a tad too high, it’s not of extreme concernRead MoreCardiovascular Disease : A Type Of Blood Vessel Disorder Essay1640 Words   |  7 Pagesdisease. The leading type of cardiovascular disease is Coronary Artery Disease (CAD) and it accounts for the majority of these deaths. Coronary Artery disease is a type of blood vessel disorder that is included in the general category of Atherosclerosis. Atherosclerosis is often referred to as â€Å"hardening of the arteries.† (Lewis, 2011) Individuals with CAD have genetic predisposition. Familial hypercholesterolemia, meaning high cholesterol in the blood, has been linked with CAD at early ages. In majority